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Gut microbiota metagenomic test

Determine your bacterial capital

This test allows defining the bacteria that populate your intestines. Your balance of protective, inflammatory and fermenting bacteria will have a major impact on your physical and psychological state.

Immunity, digestion, bloating, gas, cognitive capacity and even the quality of your sleep are all strongly affected by your intestinal microbiota (all the bacteria in your intestine).

What does the test include?

  • Home-delivered sample collection kit

  • Analysis of your samples by our functional biology medical laboratory

  • Receipt of your test results and their comprehensible explanations

  • Recommendations for diet and supplementation, together with a personalised programme based on your analysis results.

Download the e-book



Want to find out if this test is right for you?

Take the quiz

Gut microbiota metagenomic test

Determine your bacterial capital

This test allows defining the bacteria that populate your intestines. Your balance of protective, inflammatory and fermenting bacteria will have a major impact on your physical and psychological state.

Immunity, digestion, bloating, gas, cognitive capacity and even the quality of your sleep are all strongly affected by your intestinal microbiota (all the bacteria in your intestine).

What does the test include?

  • Home-delivered sample collection kit

  • Analysis of your samples by our functional biology medical laboratory

  • Receipt of your test results and their comprehensible explanations

  • Recommendations for diet and supplementation, together with a personalised programme based on your analysis results.

Download the e-book



Want to find out if this test is right for you?

Take the quiz

Bacteria analyzed

Bacteria known as protective bacteria perform a number of important functions for your health.

  1. They ensure that the intestinal wall is in good condition:

    - The intestinal wall is your intestine's filter. It does not allow substances to pass through that could be toxic, inflammatory, allergic, that could create autoimmune reactions.

    - They nourish your intestinal wall, allowing it to function properly, i.e. to produce enzymes to digest lactose or histamine from food, for example.

    - A healthy intestinal wall also allows you to properly absorb the vitamins and minerals you eat and avoid deficiencies.

  2. They oppose the development of harmful bacteria. By producing bacteriocins (substances to kill harmful bacteria) or by creating a chemical climate that is not conducive to the development of bad bacteria.

  3. They modulate our immune system to promote an appropriate response, i.e. a response that is both sufficient without being excessive.

Fermentation bacteria are gas-producing bacteria:

  1. Bacteria producing sulphur (H2S):
    These bacteria produce gas, which can generate digestive discomfort. They destroy the mucus that protects your intestinal wall, making it impermeable. These bacteria work against the efforts of Protective bacteria.

  2. methane (CH4)-producing bacteria:
    Like H2S-producing bacteria, these bacteria generate gas and destroy the mucus in your intestinal wall. An excess of these bacteria is correlated with an excessive proliferation of Candida fungi (candidiasis), often confused with gluten intolerance due to the similarity of symptoms. The way in which the problem is tackled is different in the case of candidiasis. Find out more about candida metabolite analysis.

    In excess, these bacteria participate in a Super-Extractor microbiota making weight loss difficult because it transforms complex sugars into simple sugars (learn more in the next section "Complicated weight loss?").

Bacteria known as inflammatory bacteria perform a number of functions that are harmful to your health when present in excessive quantities:

  1. Inflammation of certain mucous membranes (such as the vaginal mucosa).

  2. Systemic inflammation (polyarthritis, rheumatoid).

  3. The production and circulation of toxic compounds

  4. The development of chronic inflammatory bowel disease

  5. Metabolic disorders associated with low-grade inflammation.

This inflammation will be even greater if you have both a lot of inflammation bacteria and few protection bacteria.

Microbiota and weight gain

Why do some people find it harder to lose weight than others?

We all have different microbiota. Some people have an imbalance in their microbiota that makes weight loss difficult.


We all have different microbiota.

Certain fermentation bacteria transform complex sugars into simple sugars. Simple sugars are very quickly absorbed by your body, in excessive quantities, and make you put on weight. It's as if you eat vegetables and fruit and your body digests them like sweets. To give you an example, when you eat an apple, because of your Super-Extractor microbiota, the apple is assimilated in the same way as a biscuit and makes you fat.

  1. When toxins present on certain intestinal bacteria cross your
    intestinal tract, they will stimulate the production of inflammatory substances (cytokines). Inflammation will cause excessive production of insulin, which leads to weight gain.

  2. Insulin is a hormone that moves sugar from the blood into the cells. This ensures that there isn't too much sugar in the blood and that the blood doesn't look like syrup.

  3. This is the result of a twofold imbalance in the microbiota:

    - An excess of inflammation bacteria, releasing toxins responsible for inflammation.

    - A low level of protective bacteria that ensure good quality of the intestinal wall. The wall becoming hyperpermeable encourages the passage of these toxins to the rest of the body.

FAQ

What's the difference with a health check?

The tests offered are not those required as part of a basic check-up. These basic check-ups are designed to rule out an illness (such as an infection, a generalised infection, hepatitis, a virus, anaemia, etc.) and not to assess any malfunctions in the body that may be at the root of chronic symptoms;

Why haven't these analyses been offered to you yet?

These analyses help to identify the causes of chronic discomfort rather than acute illness. Doctors recommend general health check-ups to detect acute or sub-acute illnesses. In the case of chronic discomforts, these check-ups generally offer no solutions;


The use of these analyses requires specific knowledge of functional biology. They are therefore generally recommended by doctors with training in the field - which is not yet the case for all referring doctors.

What is chronic discomfort?

Chronic discomfort is characterised by a number of factors: 

  • The cause cannot be detected in a general health check-up and there is no precise drug treatment

  • They disrupt our quality of life considerably

  • We don't die from them

  • The treatments tried have not been effective

Why do we use 16S RNA sequencing analysis to analyse the composition of the gut microbiota rather than shotgun analysis?

The 16S RNA sequencing method makes it possible to identify a very large number (several hundred) of bacteria (genus and species), including all the bacteria of current interest (those whose names are known, their role in health and the means of modulating their numbers). The quality and depth of the sequencing will also have an impact on the number of bacterial species that can be identified.


The usefulness of the shotgun method in practice has not been demonstrated, as it allows a greater number of species to be identified, but the majority of the additional species are in fact DNA fragments that will be referred to as "unknown" and whose role is not known;


In addition, 16S ribosomal RNA (16S rRNA) allows us to maintain a certain stability over time, which is essential for comparing an individual to a population. The genes encoding 16S RNA are known as 16S rDNA and their sequence is widely used in phylogeny to reconstruct the evolutionary history of organisms, since its relatively slow rate of evolution makes it possible to establish ancient genetic divergences.

Download the e-book



Want to find out if this test is right for you?

Take the quiz

What is the difference with a health check?

The tests offered are not those required as part of a basic check-up. These basic check-ups are designed to rule out an illness (such as an infection, a generalised infection, hepatitis, a virus, anaemia, etc.) and not to assess any malfunctions in the body that may be at the root of chronic symptoms;

Why haven't these analyses been offered to you yet?

These analyses help to identify the causes of chronic discomfort rather than acute illness. Doctors recommend general health check-ups to detect acute or sub-acute illnesses. In the case of chronic discomforts, these check-ups generally offer no solutions;


The use of these analyses requires specific knowledge of functional biology. They are therefore generally recommended by doctors with training in the field - which is not yet the case for all referring doctors.

What is chronic discomfort?

Chronic discomfort is characterised by several factors: 

  1. The cause cannot be detected in a general health check-up and there is no precise drug treatment

  2. They disrupt our quality of life considerably

  3. We don't die from them

  4. The treatments tried have not been effective

Why do we use 16S RNA sequencing analysis to analyse the composition of the gut microbiota rather than shotgun analysis?

The 16S RNA sequencing method makes it possible to identify a very large number (several hundred) of bacteria (genus and species), including all the bacteria of current interest (those whose names are known, their role in health and the means of modulating their numbers). The quality and depth of the sequencing will also have an impact on the number of bacterial species that can be identified.


The usefulness of the shotgun method in practice has not been demonstrated, as it allows a greater number of species to be identified, but the majority of the additional species are in fact DNA fragments that will be referred to as "unknown" and whose role is not known;


In addition, 16S ribosomal RNA (16S rRNA) allows us to maintain a certain stability over time, which is essential for comparing an individual to a population. The genes encoding 16S RNA are known as 16S rDNA and their sequence is widely used in phylogeny to reconstruct the evolutionary history of organisms, since its relatively slow rate of evolution makes it possible to establish ancient genetic divergences.

Download the e-book



Want to find out if this test is right for you?

Take the quiz